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Article

Capture-based targeted sequencing using a T-cell control in myeloid malignancies and idiopathic cytopenias.

British journal of haematology - 1 Apr 2024

Pietka Grzegorz, De Lord Corinne, Matthias Gwynn, Cheung Betty, Atwal Sangeeta, Furtado Michelle, Cullis Jonathan, Grey-Davies Liz, Narayanan Srinivasan, McGregor Andrew, Kilner Mari, Bosworth Jenny, McMullin Mary Frances, Coats Thomas, Parcharidou Agapi, Cavenagh Jamie, Byrne Jenny, Iyengar Sunil, Mohammed Kabir, Cross Nicholas, Hubank Mike, Ribeiro Sara, Khorashad Jamshid, Wren Dorte, O'Connor Simon, Taussig David

Abstract excerpt

We report on a study of next-generation sequencing in 257 patients undergoing investigations for cytopenias. We sequenced bone marrow aspirates using a target enrichment panel comprising 82 genes and used T cells from paired blood as a control. One hundred and sixty patients had idiopathic cytopenias, 81 had myeloid malignancies and 16 had lymphoid malignancies or other diagnoses. Forty-seven of the 160 patients...

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Identifiers

PMID: 38462984
DOI: 10.1111/bjh.19377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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