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Article

The diagnostic utility of targeted gene panel sequencing in discriminating etiologies of cytopenia

27 Jul 2019

Abstract excerpt

The diagnostic utility of somatic mutations in the context of cytopenias is unclear: clonal hematopoiesis can be found in healthy individuals, patients with aplastic anemia (AA), clonal cytopenia of undetermined significance (CCUS) and myelodysplastic syndrome (MDS). We examined a cohort of 207 well-characterized cytopenic patients with a 640-gene next generation sequencing (NGS) panel and compared its diagnostic...

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PMID: 31350794
DOI: 10.1002/ajh.25592

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