Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies.

doi:10.3324/haematol.2024.285054

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Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies.

Haematologica - 1 Oct 2024

Krystel-Whittemore Melissa, Petrova-Drus Kseniya, Ptashkin Ryan N, Ewalt Mark D, Yao JinJuan, Liu Ying, Zhu Menglei, Benhamida Jamal, Durham Benjamin, Kumar Jyoti, Nafa Khedoudja, Kiecka Iwona, Bowman Anita S, Gedvilaite Erika, Casanova Jacklyn, Lin Yun-Te, Mohanty Abhinita S, Rana Satshil, Rema Anoop Balakrishnan, Rijo Ivelise, Chaves Nelio, Salazar Paulo, Yun Anita, Lachhander Sean, Wang Wei, Haque Mohammad S, Xiao Wenbin, Roshal Mikhail, Giralt Sergio, Salles Gilles, Rampal Raajit, Stein Eytan M, Perales Miguel-Angel, Horwitz Steven, Jakubowski Ann, Ponce Doris, Markova Alina, Birsoy Ozge, Mandelker Diana, Mantha Simon, Dogan Ahmet, Benayed Ryma, Ladanyi Marc, Berger Michael F, Brannon A Rose, Zehir Ahmet, Vanderbilt Chad, Arcila Maria E

Abstract excerpt

Comprehensive genomic sequencing is becoming a critical component in the assessment of hematologic malignancies, with broad implications for patients' management. In this context, unequivocally discriminating somatic from germline events is challenging but greatly facilitated by matched analysis of tumor:normal pairs of samples. In contrast to solid tumors, in hematologic malignancies conventional sources of...

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Identifiers

PMID: 38450530
DOI: 10.3324/haematol.2024.285054
PMCID: PMC11443392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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