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Article

When are idiopathic and clonal cytopenias of unknown significance (ICUS or CCUS)?

Hematology. American Society of Hematology. Education Program - 10 Dec 2021

Osman Afaf E W G

Abstract excerpt

Rapid advances in sequencing technology have led to the identification of somatic mutations that predispose a significant subset of the aging population to myeloid malignancies. Recently recognized myeloid precursor conditions include clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of unknown significance (CCUS). These conditions can present diagnostic challenges and produce...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34889436
DOI: 10.1182/hematology.2021000272
PMCID: PMC8791167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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