Article
A predictive model for bone marrow disease in cytopenia based on noninvasive procedures.
Blood advances - 14 Jun 2022
Træden Dicte, Tulstrup Morten, Cowland Jack Bernard, Sjö Lene Dissing, Bøgsted Martin, Grønbæk Kirsten, Andersen Mette Klarskov, Hansen Jakob Werner
Abstract excerpt
Bone marrow specimens are the core of the diagnostic workup of patients with cytopenia. To explore whether next-generation sequencing (NGS) could be used to rule out malignancy without bone marrow specimens, we incorporated NGS in a model to predict presence of disease in the bone marrow of patients with unexplained cytopenia. We analyzed the occurrence of mutations in 508 patients with cytopenia, referred for...
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