Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness.

PloS one - 1 Jan 2020

Ahsan Tamim, Urmi Nusrat Jahan, Sajib Abu Ashfaqur

Abstract excerpt

Interethnic variability in drug response arises from genetic differences associated with drug metabolism, action and transport. These genetic variations can affect drug efficacy as well as cause adverse drug reactions (ADRs). We retrieved drug-response related single nucleotide polymorphism (SNP) associated data from databases and analyzed to elucidate population specific distribution of 159 drug-response related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cluster Analysis
Share to Genetic Heterogeneity
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Geography

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Multivariate Analysis

Share to Pharmaceutical Preparations

Source

Open in PubMed Open full text

Identifiers

PMID: 31971968
DOI: 10.1371/journal.pone.0228000
PMCID: PMC6977754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness.PMID 31971968Read ↗

Genetic diversity of variants involved in drug response among Tunisian and Italian populations toward personalized medicine.Semantic proximity Read ↗

Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent.Semantic proximity Read ↗

Pharmacogenetic landscape of Metabolic Syndrome components drug response in Tunisia and comparison with worldwide populations.Semantic proximity Read ↗

Rare genetic variants in cellular transporters, metabolic enzymes, and nuclear receptors can be important determinants of interindividual differences in drug response.Semantic proximity Read ↗

Translational Pharmacogenomics: Discovery, Evidence Synthesis and Delivery of Race‐Conscious MedicineSemantic proximity Read ↗

Exploration of interethnic variation and repurposed drug efficacy in the treatment of SARS-CoV-2 Infection (COVID-19)Semantic proximity Read ↗

Pharmacogenomics, ancestry and clinical decision making for global populations.Semantic proximity Read ↗

Progress in understanding the genomic basis for adverse drug reactions: a comprehensive review and focus on the role of ethnicity.Semantic proximity Read ↗

Clinical Impact of Genetic Variants of Drug Transporters in Different Ethnic Groups within and Across RegionsSemantic proximity Read ↗

Clinically Actionable Pharmacogenomic Variants for Anticancer Therapy in Nigeria: First Comprehensive Variant Profiling in Underrepresented Nigerian CohortsSemantic proximity Read ↗

CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized TherapySemantic proximity Read ↗

Pharmacogenomics in Asian Subpopulations and Impacts on Commonly Prescribed MedicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.