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Article

Pharmacogenomic profile of a central European urban random population-Czech population.

PloS one - 1 Jan 2023

Proietti Riccardo, Maranho Neto Geraldo A, Kunzova Sarka, Lo Re Oriana, Ahola-Olli Ari, Heliste Juho, Gonzalez-Rivas Juan Pablo, Vinciguerra Manlio

Abstract excerpt

The genetic basis of variability in drug response is at the core of pharmacogenomics (PGx) studies, aiming at reducing adverse drug reaction (ADR), which have interethnic variability. This study used the Kardiovize Brno 2030 random urban Czech sample population to analyze polymorphisms in a wide spectrum of genes coding for liver enzymes involved in drug metabolism. We aimed at correlating real life drug...

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Identifiers

PMID: 37079615
DOI: 10.1371/journal.pone.0284386
PMCID: PMC10118108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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