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Article

Pharmacogenomic landscape of a Moroccan cohort: enhancing global diversity and addressing the North African gap.

Scientific reports - 21 May 2026

Kartti Souad, Chemao-Elfihri Mohammed Walid, Hakmi Mohammed, Aherkou Marouane, ElJaoudi Rachid, Balouch Lahcen, Fahime Elmostafa El, Belyamani Lahcen, Boutayeb Saber

Abstract excerpt

Pharmacogenomics (PGx) enables personalized therapy by considering individual genetic variation. However, North African populations remain underrepresented in global PGx databases despite their substantial and unique genetic diversity, which can strongly influence drug response. This study characterizes the pharmacogenomic landscape of 109 Moroccan individuals using whole-genome sequencing data. Across 8289...

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Identifiers

PMID: 42168535
DOI: 10.1038/s41598-026-54350-1
PMCID: PMC13402624

Genes

CYP2C19
SLCO1B1
DPYD
UGT1A1
VKORC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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