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Article

Calcitonin gene-related peptide-modulated macrophage phenotypic alteration regulates angiogenesis in early bone healing.

International immunopharmacology - 30 Mar 2024

Kong Qingci, Gao Siyong, Li Pugeng, Sun Hanyu, Zhang Zhengchuan, Yu Xiaolin, Deng Feilong, Wang Tianlu

Abstract excerpt

OBJECTIVES: This study aimed to investigate the effect of calcitonin gene-related peptide (CGRP) on the temporal alteration of macrophage phenotypes and macrophage-regulated angiogenesis duringearlybonehealing and preliminarily elucidate the mechanism. METHODS: In vivo, the rat mandibular defect models were established with inferior alveolar nerve transection (IANT) or CGRP receptor antagonist injection....

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Source

Identifiers

PMID: 38452411
DOI: 10.1016/j.intimp.2024.111766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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