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Monocyte Chemoattractant Protein-1 from a Conditioned Medium of Bone Marrow-Derived Mesenchymal Stem Cells Promotes Bone Regeneration by Enhancing Macrophage Phenotype Switching

2025-01-07

Abstract excerpt

<h4>Objectives: </h4> Cytokines and chemokines contained in conditioned media from human bone marrow-derived mesenchymal stem cells (MSC-CM) promote bone regeneration. We recently reported macrophage phenotype switching towards the anti-inflammatory M2 phenotype induced by MSC-CM and its potential to promote bone regeneration. However, the specific factors in the MSC-CM responsible for this process remain unclear....

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Literature Corpus work: be47bdd0-2080-5ed4-bbe2-0d206fe495af
DOI: 10.20944/preprints202501.0443.v1

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