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Article

Macrophage phenotype in the epigallocatechin-3-gallate (EGCG)-modified collagen determines foreign body reaction.

Journal of tissue engineering and regenerative medicine - 1 Jun 2018

Chu Chenyu, Liu Li, Wang Yufei, Wei Shimin, Wang Yuanjing, Man Yi, Qu Yili

Abstract excerpt

Collagen has been widely used in guided bone regeneration, and the implantation of collagen membranes will elicit the foreign body reaction (FBR). The imbalance of FBR often leads to failure of dental implants. Therefore, modulation of the FBR after implantation of collagen membranes becomes increasingly important. Macrophages, pivotal in FBR, have been distinguished into pro-inflammatory (M1) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29704322
DOI: 10.1002/term.2687

Genes

CCL2
CCL3
CCR2
CCR3
CXCL1
STAB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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