Article
Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome.
Genetics - 1 Jun 2015
Pinter Stefan F, Colognori David, Beliveau Brian J, Sadreyev Ruslan I, Payer Bernhard, Yildirim Eda, Wu Chao-Ting, Lee Jeannie T
Abstract excerpt
In mammals, several classes of monoallelic genes have been identified, including those subject to X-chromosome inactivation (XCI), genomic imprinting, and random monoallelic expression (RMAE). However, the extent to which these epigenetic phenomena are influenced by underlying genetic variation is unknown. Here we perform a systematic classification of allelic imbalance in mouse hybrids derived from reciprocal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.