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Article

Role of seasonal importation and genetic drift on selection for drug-resistant genotypes of Plasmodium falciparum in high-transmission settings.

Journal of the Royal Society, Interface - 1 Mar 2024

Zupko Robert J, Servadio Joseph L, Nguyen Tran Dang, Tran Thu Nguyen-Anh, Tran Kien Trung, Somé Anyirékun Fabrice, Boni Maciej F

Abstract excerpt

Historically Plasmodium falciparum has followed a pattern of drug resistance first appearing in low-transmission settings before spreading to high-transmission settings. Several features of low-transmission regions are hypothesized as explanations: higher chance of symptoms and treatment seeking, better treatment access, less within-host competition among clones and lower rates of recombination. Here, we test...

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Identifiers

PMID: 38442861
DOI: 10.1098/rsif.2023.0619
PMCID: PMC10914515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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