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Assessing emergence risk of double-resistant and triple-resistant genotypes of Plasmodium falciparum.

Nature communications - 15 Feb 2024

Li Eric Zhewen, Nguyen Tran Dang, Tran Thu Nguyen-Anh, Zupko Robert J, Boni Maciej F

Abstract excerpt

Delaying and slowing antimalarial drug resistance evolution is a priority for malaria-endemic countries. Until novel therapies become available, the mainstay of antimalarial treatment will continue to be artemisinin-based combination therapy (ACT). Deployment of different ACTs can be optimized to minimize evolutionary pressure for drug resistance by deploying them as a set of co-equal multiple first-line...

Topics

Humans
Antimalarials
Drug Resistance
Folic Acid Antagonists
Genotype
Malaria
Malaria, Falciparum
Plasmodium falciparum

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38360803
DOI: 10.1038/s41467-024-45547-x
PMCID: PMC10869733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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