Article

Immune selection suppresses the emergence of drug resistance in malaria parasites but facilitates its spread

2020-12-15

Abstract excerpt

Although drug resistance in Plasmodium falciparum typically evolves in regions of low transmission, resistance spreads readily following introduction to regions with a heavier disease burden. This suggests that the origin and the spread of resistance are governed by different processes, and that high transmission intensity specifically impedes the origin. Factors associated with high transmission, such as highly...

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Literature Corpus work: 95c9d504-a05b-57e7-b381-f4d2ac43bf8a
DOI: 10.1101/2020.12.15.422843

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