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An AI ‐assisted integrated, scalable, single‐cell phenomic‐transcriptomic platform to elucidate intratumor heterogeneity against immune response

2 Jan 2024

Abstract excerpt

Abstract We present a novel framework combining single‐cell phenotypic data with single‐cell transcriptomic analysis to identify factors underpinning heterogeneity in antitumor immune response. We developed a pairwise, tumor‐immune discretized interaction assay between natural killer (NK‐92MI) cells and patient‐derived head and neck squamous cell carcinoma (HNSCC) cell lines on a microfluidic cell‐trapping...

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PMID: 38435825
DOI: 10.1002/btm2.10628

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