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Article

An innovative single-cell approach for phenotyping and functional genotyping of CAR NK cells.

Journal for immunotherapy of cancer - 31 May 2024

Sullivan Matthew Ryan, Finocchiaro Michael, Yang Yichao, Thomas Judene, Ali Alaa, Kaplan Isabel, Abdulhamid Yasmin, Bobilev Eden, Sheffer Michal, Romee Rizwan, Konry Tania

Abstract excerpt

BACKGROUND: To accelerate the translation of novel immunotherapeutic treatment approaches, the development of analytic methods to assess their efficacy at early in vitro stages is necessary. Using a droplet-based microfluidic platform, we have established a method for multiparameter quantifiable phenotypic and genomic observations of immunotherapies. Chimeric antigen receptor (CAR) natural killer (NK) cells are...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Immunotherapy, Adoptive

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Source

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Identifiers

PMID: 38821719
DOI: 10.1136/jitc-2024-008912
PMCID: PMC11149162

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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