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An EWAS of dementia biomarkers and their associations with age, African ancestry, and PTSD

2 Mar 2024

Abstract excerpt

BACKGROUND: Large-scale cohort and epidemiological studies suggest that PTSD confers risk for dementia in later life but the biological mechanisms underlying this association remain unknown. This study examined this question by assessing the influences of PTSD, APOE ε4 genotypes, DNA methylation, and other variables on the age- and dementia-associated biomarkers Aβ40, Aβ42, GFAP, NfL, and pTau-181 measured in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38431614
DOI: 10.1186/s13148-024-01649-3

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