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Rare variants in <i>IFFO1, DTNB</i> and <i>NLRC3</i> associate with Alzheimer’s disease CSF profile of neuronal injury and inflammation

2021-07-14

Abstract excerpt

Alzheimer’s disease (AD) biomarkers represent several neurodegenerative processes, such as synaptic dysfunction, neuronal inflammation and injury, as well as amyloid pathology. We performed an exome-wide rare variant analysis of six AD biomarkers (β-amyloid, total/phosphorylated tau, Nfl, YKL-40, and Neurogranin) to discover genes associated with these markers. Genetic and biomarker information was available for 4...

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Literature Corpus work
c893b775-4f37-553d-ad88-ba74693e6982
DOI
10.1101/2021.07.10.21260177
Open publication

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Rare variants in <i>IFFO1, DTNB</i> and <i>NLRC3</i> associate with Alzheimer’s disease CSF profile of neuronal injury and inflammationDOI 10.1101/2021.07.10.21260177
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