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Article

Structural–functional diversity of CD47 proteoforms

14 Feb 2024

Abstract excerpt

The ubiquitously expressed transmembrane glycoprotein CD47 participates in various important physiological cell functions, including phagocytosis, apoptosis, proliferation, adhesion, and migration, through interactions with its ligands, including the inhibitory receptor signal regulatory protein α (SIRPα), secreted glycoprotein thrombospondin-1 (TSP-1), and integrins. Elevated expression of CD47 is observed in a...

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PMID: 38426113
DOI: 10.3389/fimmu.2024.1329562

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