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Role of CD47 in tumor immunity: a potential target for combination therapy

13 Jun 2022

Abstract excerpt

CD47 performs a vital function in cancer therapy by binding to different SIRPα, thrombospondin 1, and integrin. However, its role in tumor immunity and its correlation with prognosis among many cancer types remain unknown. The raw mRNA expression data of CD47 in cancer patients was downloaded from TCGA and GTEx datasets. The protein expression of CD47 was detected using a microarray. Kaplan Meier analysis and...

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PMID: 35697717
DOI: 10.1038/s41598-022-13764-3

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