Article
A multidimensional pan-cancer analysis of CD47 and its role in promoting malignant phenotype in pancreatic adenocarcinoma.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Aug 2026
Su Shuangyan, Wu Bihua, Li Yuwei, Wang XianYu, Lou Fenglin, Mei Zhenghao, Guo Le
Abstract excerpt
BACKGROUND: CD47 is a widely expressed member of the immunoglobulin superfamily and plays important roles in cell proliferation, adhesion, and immune evasion. Previous studies have shown that CD47 contributes to tumor development by inhibiting immune-mediated clearance in multiple cancer types. However, the expression patterns of CD47 across different malignancies, its prognostic relevance, and its associations...
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