Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Significance of CD47 and Its Association With Tumor Immune Microenvironment Heterogeneity in Ovarian Cancer

12 Dec 2021

Abstract excerpt

Background: It was reported that tumor heterogeneity and the surrounding tumor microenvironment (TME) in ovarian cancer affects immunotherapy efficacy and patient outcomes. And the TME of ovarian cancer is intrinsically heterogeneous. CD47 plays vital roles in cell functional behavior and immune homeostasis relating to cancer prognosis. But how it affects TME and its contribution to heterogeneity in ovarian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Immunotherapy and Immune Responses
Share to Phagocytosis and Immune Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34966389
DOI: 10.3389/fimmu.2021.768115

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Significance of CD47 and Its Association With Tumor Immune Microenvironment Heterogeneity in Ovarian CancerPMID 34966389Read ↗

Role of CD47 in tumor immunity: a potential target for combination therapySemantic proximity Read ↗

Integrative Multi-Omics and Machine Learning Approach Reveals Tumor Microenvironment-Associated Prognostic Biomarkers in Ovarian CancerSemantic proximity Read ↗

A multidimensional pan-cancer analysis of CD47 and its role in promoting malignant phenotype in pancreatic adenocarcinoma.Semantic proximity Read ↗

Ovarian cancer‐specific dysregulated genes with prognostic significance: scRNA‐Seq with bulk RNA‐Seq data and experimental validationSemantic proximity Read ↗

Characterizing intra- and inter-tumor heterogeneity in Ovarian high-grade serous carcinoma subtypes using single-cell and spatial transcriptomicsSemantic proximity Read ↗

Single-cell analysis reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of ovarian cancerSemantic proximity Read ↗

New insights into tumor immunity revealed by the unique genetic and genomic aspects of ovarian cancer.Semantic proximity Read ↗

Exploring tumor microenvironment in molecular subtyping and prognostic signatures in ovarian cancer and identification of SH2D1A as a key regulator of ovarian cancer carcinogenesisSemantic proximity Read ↗

Unraveling Tumor-Immune Heterogeneity in Advanced Ovarian Cancer Uncovers Immunogenic Effect of ChemotherapySemantic proximity Read ↗

High Tumor-Infiltrating Lymphocyte Count Is Associated with Distinct Gene Expression Profile and Longer Patient Survival in Advanced Ovarian CancerSemantic proximity Read ↗

Role of CD47 gene expression in colorectal cancer: a comprehensive molecular profiling studySemantic proximity Read ↗

Isoform switching of CD47 induces macrophage-initiated cancer cell pyroptosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.