Article
Protein engineering for thermostability.
Trends in biotechnology - 1 Jan 1990
Nosoh Y, Sekiguchi T
Abstract excerpt
Studies with small, monomeric proteins indicate that, to some extent, the effects of amino acid substitutions can be predicted. However, conformational and other changes may complicate the prediction. Site-directed mutagenesis is leading both to a better understanding of protein stability and to the production of more stable proteins.
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