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Article

Hnrnpk protects against osteoarthritis through targeting WWC1 mRNA and inhibiting Hippo signaling pathway

26 Feb 2024

Abstract excerpt

Osteoarthritis (OA) is an age-related or post-traumatic degenerative whole joint disease characterized by the rupture of articular cartilage homeostasis, the regulatory mechanisms of which remain elusive. This study identifies the essential role of heterogeneous nuclear ribonucleoprotein K (hnRNPK) in maintaining articular cartilage homeostasis. Hnrnpk expression is markedly downregulated in human and mice OA...

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PMID: 38414246
DOI: 10.1016/j.ymthe.2024.02.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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