Article
Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria.
Proceedings of the National Academy of Sciences of the United States of America - 24 Oct 2017
Couce Alejandro, Caudwell Larissa Viraphong, Feinauer Christoph, Hindré Thomas, Feugeas Jean-Paul, Weigt Martin, Lenski Richard E, Schneider Dominique, Tenaillon Olivier
Abstract excerpt
Understanding the extreme variation among bacterial genomes remains an unsolved challenge in evolutionary biology, despite long-standing debate about the relative importance of natural selection, mutation, and random drift. A potentially important confounding factor is the variation in mutation rates between lineages and over evolutionary history, which has been documented in several species. Mutation...
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