Article
Genome-wide mutational diversity in an evolving population of Escherichia coli.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2009
Barrick J E, Lenski R E
Abstract excerpt
The level of genetic variation in a population is the result of a dynamic tension between evolutionary forces. Mutations create variation, certain frequency-dependent interactions may preserve diversity, and natural selection purges variation. New sequencing technologies offer unprecedented opportunities to discover and characterize the diversity present in evolving microbial populations on a whole-genome scale....
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