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Article

Epigenetic Targeting to Overcome Radioresistance in Head and Neck Cancer

9 Feb 2024

Abstract excerpt

(1) Background: The sensitivity of head and neck squamous cell carcinoma (HNSCC) to ionizing radiation, among others, is determined by the number of cells with high clonogenic potential and stem-like features. These cellular characteristics are dynamically regulated in response to treatment and may lead to an enrichment of radioresistant cells with a cancer stem cell (CSC) phenotype. Epigenetic mechanisms,...

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PMID: 38398123
DOI: 10.3390/cancers16040730

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