Article
Prevalence of persistent SARS-CoV-2 in a large community surveillance study.
Nature - 1 Feb 2024
Ghafari Mahan, Hall Matthew, Golubchik Tanya, Ayoubkhani Daniel, House Thomas, MacIntyre-Cockett George, Fryer Helen R, Thomson Laura, Nurtay Anel, Kemp Steven A, Ferretti Luca, Buck David, Green Angie, Trebes Amy, Piazza Paolo, Lonie Lorne J, Studley Ruth, Rourke Emma, Smith Darren L, Bashton Matthew, Nelson Andrew, Crown Matthew, McCann Clare, Young Gregory R, Santos Rui Andre Nunes Dos, Richards Zack, Tariq Mohammad Adnan, Cahuantzi Roberto, Barrett Jeff, Fraser Christophe, Bonsall David, Walker Ann Sarah, Lythgoe Katrina
Abstract excerpt
Persistent SARS-CoV-2 infections may act as viral reservoirs that could seed future outbreaks1-5, give rise to highly divergent lineages6-8 and contribute to cases with post-acute COVID-19 sequelae (long COVID)9,10. However, the population prevalence of persistent infections, their viral load kinetics and evolutionary dynamics over the course of infections remain largely unknown. Here, using viral sequence data...
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