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Article

Genomic and epidemiologic characteristics of SARS-CoV-2 persistent infections in California, January 2021 - July 2023.

PLoS pathogens - 1 Nov 2025

Bell John M, Elder Jesse, Ryder Rahil, Smith Emily A, Scribner Michelle, Gilliam Sabrina, Borthwick Deva, Crumpler Megan, Skarbinski Jacek, Morales Christina, Wadford Debra A

Abstract excerpt

Novel SARS-CoV-2 variants demonstrating considerable intra-host evolution emerged throughout the pandemic. The persistent infections thought to give rise to these variants, however, have been difficult to identify at scale. This study sought to detect and characterize persistent infection cases in California using routine epidemiologic and genomic surveillance data. We identified 69 persistent infection cases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41212906
DOI: 10.1371/journal.ppat.1013365
PMCID: PMC12614806

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