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Article

SIRT7: a novel molecular target for personalized cancer treatment?

21 Feb 2024

Abstract excerpt

-dependent enzymes assumes a pivotal role in orchestrating adaptive responses to environmental fluctuations and stress stimuli, operating at both genomic and metabolic levels. Within this family, SIRT7 emerges as a versatile player in tumorigenesis, displaying both pro-tumorigenic and tumor-suppressive functions in a context-dependent manner. While other sirtuins, such as SIRT1 and SIRT6, exhibit a similar dual...

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PMID: 38383727
DOI: 10.1038/s41388-024-02976-8

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