Article
Prognostic biomarker study in patients with clinical stage I esophageal squamous cell carcinoma: JCOG0502-A1.
Cancer science - 1 Mar 2022
Oshima Kotoe, Kato Ken, Ito Yoshinori, Daiko Hiroyuki, Nozaki Isao, Nakagawa Satoru, Shibuya Yuichi, Kojima Takashi, Toh Yasushi, Okada Morihito, Hironaka Shuichi, Akiyama Yuji, Komatsu Yoshito, Maejima Kazuhiro, Nakagawa Hidewaki, Onuki Ritsuko, Nagai Momoko, Kato Mamoru, Kanato Keisuke, Kuchiba Aya, Nakamura Kenichi, Kitagawa Yuko
Abstract excerpt
We undertook genomic analyses of Japanese patients with stage I esophageal squamous cell carcinoma (ESCC) to investigate the frequency of genomic alterations and the association with survival outcomes. Biomarker analysis was carried out for patients with clinical stage T1bN0M0 ESCC enrolled in JCOG0502 (UMIN000000551). Whole-exome sequencing (WES) was performed using DNA extracted from formalin-fixed,...
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