Article
A comprehensive genomic characterization of esophageal squamous cell carcinoma: from prognostic analysis to in vivo assay.
Chinese journal of cancer - 11 Aug 2016
Chen Yuan-Bin, Jia Wei-Hua
Abstract excerpt
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and is characterized by numerous genetic mutations. TNM staging is not sufficient for predicting patient outcomes. Additionally, ESCC shows poor responsiveness to chemotherapy and radiation. Thus, there is an urgent need to find efficient therapy targets. Previous ESCC high-throughput genomic studies have lacked...
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