Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Highly Sensitive Detection of T790 M with a Three-Level Characteristic Current by Thymine-Hg(II)-Thymine in the α-Hemolysin Nanopore.

Analytical chemistry - 27 Feb 2024

Li Yaping, Yang Yongqi, Zhong Chunmeng, Xiao Dan, Zhou Cuisong

Abstract excerpt

Sensitive detection of resistance mutation T790 M is of great significance for early diagnosis and prognostic monitoring of non-small-cell lung cancer (NSCLC). In this paper, we showed a highly sensitive detection strategy for T790 M using a three-level characteristic current signal pattern in an α-hemolysin nanopore. A probe was designed that formed a C-T mismatched base pair with wild-type/P and a T-T...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemolysin Proteins

Share to Lung Neoplasms

Share to Mercury

Share to Nanopores

Share to Protein Kinase Inhibitors

Share to Thymine

Source

Identifiers

PMID: 38372205
DOI: 10.1021/acs.analchem.3c05571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Highly Sensitive Detection of T790 M with a Three-Level Characteristic Current by Thymine-Hg(II)-Thymine in the α-Hemolysin Nanopore.PMID 38372205Read ↗

Direct Read and Quantify Damage Nucleotide from an Oligonucleotide Using a Single Molecule InterfaceSemantic proximity Read ↗

Early Monitoring Drug Resistant Mutation T790M with a Two-Dimensional Simultaneous Discrimination Nanopore Strategy.Semantic proximity Read ↗

Nanopore-Based Strategy for Single-Nucleotide Mutation Detection in Sickle Cell Disease Using Anthracycline Probes.Semantic proximity Read ↗

Label-Free Detection of DNA Mutations by Nanopore Analysis.Semantic proximity Read ↗

Engineering of a DNA/γPNA Hybrid Nanoreporter for ctDNA Mutation Detection via γPNA Urinalysis.Semantic proximity Read ↗

Nanozyme-Enhanced Paper-Based Bipolar Electrode Biosensor for Dual-Mode Detection for M918T in Serum with Single-Base Specificity.Semantic proximity Read ↗

One-by-one single-molecule detection of mutated nucleobases by monitoring tunneling current using a DNA tip.Semantic proximity Read ↗

Sequence-specific detection of individual DNA strands using engineered nanopores.Semantic proximity Read ↗

Direct MYD88L265P gene detection for diffuse large B-cell lymphoma (DLBCL) via a miniaturised CRISPR/dCas9-based sensing chip.Semantic proximity Read ↗

Single Locked Nucleic Acid-Enhanced Nanopore Genetic Discrimination of Pathogenic Serotypes and Cancer Driver Mutations.Semantic proximity Read ↗

Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores.Semantic proximity Read ↗

3D Blockage Mapping for Identifying Familial Point Mutations in Single Amyloid-β Peptides with a Nanopore.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.