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Article

CRISPR-Cas in Pseudomonas aeruginosa provides transient population-level immunity against high phage exposures.

The ISME journal - 8 Jan 2024

Watson Bridget N J, Capria Loris, Alseth Ellinor O, Pons Benoit J, Biswas Ambarish, Lenzi Luca, Buckling Angus, van Houte Stineke, Westra Edze R, Meaden Sean

Abstract excerpt

The prokaryotic adaptive immune system, CRISPR-Cas (clustered regularly interspaced short palindromic repeats; CRISPR-associated), requires the acquisition of spacer sequences that target invading mobile genetic elements such as phages. Previous work has identified ecological variables that drive the evolution of CRISPR-based immunity of the model organism Pseudomonas aeruginosa PA14 against its phage DMS3vir,...

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Identifiers

PMID: 38366022
DOI: 10.1093/ismejo/wrad039
PMCID: PMC10873826

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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