Article
Phylogenetic Distribution of CRISPR-Cas Systems in Antibiotic-Resistant Pseudomonas aeruginosa.
mBio - 24 Nov 2015
van Belkum Alex, Soriaga Leah B, LaFave Matthew C, Akella Srividya, Veyrieras Jean-Baptiste, Barbu E Magda, Shortridge Dee, Blanc Bernadette, Hannum Gregory, Zambardi Gilles, Miller Kristofer, Enright Mark C, Mugnier Nathalie, Brami Daniel, Schicklin Stéphane, Felderman Martina, Schwartz Ariel S, Richardson Toby H, Peterson Todd C, Hubby Bolyn, Cady Kyle C
Abstract excerpt
UNLABELLED: Pseudomonas aeruginosa is an antibiotic-refractory pathogen with a large genome and extensive genotypic diversity. Historically, P. aeruginosa has been a major model system for understanding the molecular mechanisms underlying type I clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated protein (CRISPR-Cas)-based bacterial immune system function. However, little...
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