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Article

Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases: A Mendelian Randomization Study.

JAMA network open - 4 Jan 2021

Levin Michael G, Klarin Derek, Assimes Themistocles L, Freiberg Matthew S, Ingelsson Erik, Lynch Julie, Natarajan Pradeep, O'Donnell Christopher, Rader Daniel J, Tsao Philip S, Chang Kyong-Mi, Voight Benjamin F, Damrauer Scott M

Abstract excerpt

Importance: Smoking is associated with atherosclerotic cardiovascular disease, but the relative contribution to each subtype (coronary artery disease [CAD], peripheral artery disease [PAD], and large-artery stroke) remains less well understood. Objective: To determine the association between genetic liability to smoking and risk of CAD, PAD, and large-artery stroke. Design, Setting, and Participants: Mendelian...

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Atherosclerosis
Cardiovascular Diseases
Genome-Wide Association Study
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peripheral Vascular Diseases

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Identifiers

PMID: 33464320
DOI: 10.1001/jamanetworkopen.2020.34461
PMCID: PMC7816104

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