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Article

Renal cell carcinoma risk is associated with the interactions of APOE, VHL and MTHFR gene polymorphisms.

International journal of clinical and experimental pathology - 1 Jan 2015

Lv Cai, Bai Zhiming, Liu Zhenxiang, Luo Pengcheng, Zhang Jie

Abstract excerpt

OBJECTIVE: The study was designed to explore the association of renal cell carcinoma (RCC) with VHL (rs779805), MTHFR (rs1801133) and APOE (rs8106822 and rs405509) polymorphisms, investigate the interactions among the single nucleotide polymorphisms (SNPs), and explore roles of the interactions in the pathogenesis of RCC in Chinese Han population. METHODS: 81 RCC patients and 80 healthy controls were included in...

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Source

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Identifiers

PMID: 26191297
PMCID: PMC4503168

Genes

APOE
MTHFR
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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