Article
Immune evasion by proteolytic shedding of natural killer group 2, member D ligands in Helicobacter pylori infection
21 Jan 2024
Abstract excerpt
Background Helicobacter pylori ( H. pylori ) uses various strategies that attenuate mucosal immunity to ensure its persistence in the stomach. We recently found evidence that H. pylori might modulate the natural killer group 2, member 2 (NKG2D) system. The NKG2D receptor and its ligands are a major activation system of natural killer and cytotoxic T cells, which are important for mucosal immunity and tumor...
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