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Article

Identification of the VLDLR locus associated with giant cell arteritis and the possible causal role of low-density lipoprotein cholesterol in its pathogenesis.

Rheumatology (Oxford, England) - 1 Oct 2024

Iwasaki Takeshi, Watanabe Ryu, Zhang Hui, Hashimoto Motomu, Morinobu Akio, Matsuda Fumihiko

Abstract excerpt

OBJECTIVES: To elucidate the association between genetic variants and the risk of GCA via large-scale genome-wide association studies (GWAS). In addition, to assess the causal effect of a specific molecule by employing the obtained GWAS results as genetic epidemiological tools. METHODS: We applied additional variant quality control to the publicly available GWAS results from the biobanks of the UK (UKBB) and...

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PMID: 38317496
DOI: 10.1093/rheumatology/keae075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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