Article
Influence of the IL17A locus in giant cell arteritis susceptibility.
Annals of the rheumatic diseases - 1 Sept 2014
Márquez A, Hernández-Rodríguez J, Cid M C, Solans R, Castañeda S, Fernández-Contreras M E, Ramentol M, Morado I C, Narváez J, Gómez-Vaquero C, Martínez-Taboada V M, Ortego-Centeno N, Sopeña B, Monfort J, García-Villanueva M J, Caminal-Montero L, de Miguel E, Blanco R, Palm O, Molberg O, Latus J, Braun N, Moosig F, Witte T, Beretta L, Santaniello A, Pazzola G, Boiardi L, Salvarani C, González-Gay M A, Martín J
Abstract excerpt
OBJECTIVE: Different lines of evidence have highlighted the role of IL-17A in the inflammatory process occurring in giant cell arteritis (GCA). The aim of the present study was to assess whether the IL17A locus influences GCA susceptibility and its clinical subphenotypes. METHODS: We carried out a large meta-analysis including a total of 1266 biopsy-proven GCA patients and 3779 healthy controls from four European...
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