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Article

Novel role of bone morphogenetic protein 9 in innate host responses to HCMV infection

2 Feb 2024

Abstract excerpt

Herpesviruses modulate immune control to secure lifelong infection. The mechanisms Human Cytomegalovirus (HCMV) employs in this regard can reveal unanticipated aspects of cellular signaling involved in antiviral immunity. Here, we describe a novel relationship between the TGF-β family cytokine BMP9 and HCMV infection. We identify a cross-talk between BMP9-induced and IFN receptor-mediated signaling, showing that...

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PMID: 38308064
DOI: 10.1038/s44319-024-00072-2

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