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Article

IRF6 in development and disease: A mediator of quiescence and differentiation

1 Jul 2008

Abstract excerpt

Post utero development of the mammary gland is a complex developmental process characterized by states of rapid cell proliferation (branching morphogenesis) followed by functional differentiation (lactation) and the consequent apoptosis (involution) of the secretory mammary epithelial cell. This process is cyclical, such that involution returns the mammary gland to a near-virgin-like state capable of responding...

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PMID: 18604160
DOI: 10.4161/cc.7.13.6221

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