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Article

Regulation of TGFβ and BMP signalling in human B cells by latent Epstein-Barr virus

2014-01-01

Abstract excerpt

Most individuals are infected with EBV, which establishes latent infection in B cells. Although usually asymptomatic, EBV persistence is associated with several types of lymphoma. TGFβ signals via TGFβ receptors (TGFβR) 1 and 2 and is generally pro-apoptotic and anti-proliferative, but EBV infection renders cells resistant to these effects. The aim of this thesis was to investigate further the mechanism by which t...

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Literature Corpus work
eb09f1c5-57cd-5f8c-bb36-f00346b68751
DOI
10.25560/33124
Open publication

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