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The Potential Role and Therapeutic Relevance of Cellular Senescence in Skeletal Pathophysiology

29 Jan 2024

Abstract excerpt

Biological aging profoundly impairs the homeostasis of the skeletal system. Cellular senescence, a hallmark of biological aging, plays an instrumental role in bone disease. The underlying mechanisms of cellular senescence, triggered by both intracellular and extracellular stimuli, are multifaceted and yet to be uncovered. Recent research indicates that acute cellular senescence often serves beneficial roles, such...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38306619
DOI: 10.1093/gerona/glae037

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