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Article

Family-based genetic analysis in schizophrenia by whole-exome sequence to identify rare pathogenic variants.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2024

Shang Binli, Yang Runxu, Lian Kun, Dong Lei, Liu Hongbing, Wang Tianlan, Yang Guangya, Xi Kang, Xu Xiufeng, Cheng Yuqi

Abstract excerpt

Schizophrenia (SCZ) is influenced by a combination of genetic and environmental factors. Although several studies have been conducted to identify the causative loci and genes, few of these loci or genes can be repeated due to the high phenotypic and genetic heterogeneity of disease, and their mechanisms are not fully understood. There may be some "missing heritability" that has not yet been found. In order to...

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Source

Identifiers

PMID: 38293813
DOI: 10.1002/ajmg.b.32968

Genes

PKHD1L1
PRKDC
SNAI2
ST18
TFAP2B
TFEB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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