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Article

Investigation of rare variants in LRP1, KPNA1, ALS2CL and ZNF480 genes in schizophrenia patients reflects genetic heterogeneity of the disease.

Behavioral and brain functions : BBF - 20 Feb 2013

Jouan Loubna, Girard Simon L, Dobrzeniecka Sylvia, Ambalavanan Amirthagowri, Krebs Marie-Odile, Joober Ridha, Gauthier Julie, Dion Patrick A, Rouleau Guy A

Abstract excerpt

BACKGROUND: Schizophrenia is a severe psychiatric disease characterized by a high heritability and a complex genetic architecture. Recent reports based on exome sequencing analyses have highlighted a significant increase of potentially deleterious de novo mutations in different genes in individuals with schizophrenia. FINDINGS: This report presents the mutation screening results of four candidate genes for which...

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Source

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Identifiers

PMID: 23425335
DOI: 10.1186/1744-9081-9-9
PMCID: PMC3599135

Genes

KPNA1
LRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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