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Article

RH genotype matching for transfusion support in sickle cell disease.

Blood - 13 Sept 2018

Chou Stella T, Evans Perry, Vege Sunitha, Coleman Sarita L, Friedman David F, Keller Margaret, Westhoff Connie M

Abstract excerpt

Rh alloimmunization remains a challenge for patients with sickle cell disease (SCD) despite transfusion of serologic Rh C, E, and K antigen-matched red cells. Inheritance of altered RH alleles contributes to the prevalence of Rh antibodies after blood transfusion in patients with SCD and explains approximately one-third of cases. The remainder seem to be stimulated by altered Rh proteins on African American donor...

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Topics

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Share to Alleles
Share to Anemia, Sickle Cell
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Rh-Hr Blood-Group System

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Source

Identifiers

PMID: 30026182
DOI: 10.1182/blood-2018-05-851360

Genes

SCD
RHCE
RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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