Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Current Insights to Regulation and Role of Telomerase in Human Diseases

28 Feb 2017

Abstract excerpt

The telomerase ribonucleoprotein complex has a pivotal role in regulating the proliferation and senescence of normal somatic cells as well as cancer cells. This complex is comprised mainly of telomerase reverse transcriptase (TERT), telomerase RNA component (TERC) and other associated proteins that function to elongate telomeres localized at the end of the chromosomes. While reactivation of telomerase is a major...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Research and Treatments
Share to Mesenchymal stem cell research
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28264499
DOI: 10.3390/antiox6010017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Current Insights to Regulation and Role of Telomerase in Human DiseasesPMID 28264499Read ↗

Telomeres and telomerase in oncogenesis (Review)Semantic proximity Read ↗

Human Telomerase and Its RegulationSemantic proximity Read ↗

Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancerSemantic proximity Read ↗

Telomerase in Cancer: Function, Regulation, and Clinical TranslationSemantic proximity Read ↗

Implications of telomere‐independent activities of telomerase reverse transcriptase in human cancerSemantic proximity Read ↗

Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new playersSemantic proximity Read ↗

Telomerase in human development and cancerSemantic proximity Read ↗

Telomeres and telomerase: biological and clinical importanceSemantic proximity Read ↗

Telomere and Telomerase Therapeutics in CancerSemantic proximity Read ↗

Role of Telomeres and Telomerase in Aging and CancerSemantic proximity Read ↗

Telomerase and cancerSemantic proximity Read ↗

Molecular regulation of telomerase activity in aging.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.