Article
The role of neurotrophin polymorphisms and susceptibility to neural damage in leprosy.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 May 2024
Jorge Karina Talita de Oliveira Santana, Braga Marina Pimenta, Cazzaniga Rodrigo Anselmo, Santos Camilla Natália Oliveira, Teixeira Mauro Martins, Gomes Karina Braga, de Jesus Amélia Maria Ribeiro, Soriani Frederico Marianetti
Abstract excerpt
OBJECTIVES: Mycobacterium leprae is able to infect Schwann cells leading to neural damage. Neurotrophins are involved in nervous system plasticity and impact neural integrity during diseases. Investigate the association between single nucleotide polymorphisms in neurotrophin genes and leprosy phenotypes, especially neural damage. DESIGN: We selected single nucleotide polymorphisms in neurotrophins or their...
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